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KM 09121

CAS No.: 883004-81-7

Formula: C24H21N3O

Molecular Weight: 367.44300

Suppliers: All(0) China Suppliers(0) Products(0)

Description
Basic Info
Price

What is KM 09121

**Introduction to KM 09121** The KM 09121 is a high-performance, precision-engineered component designed for durability and efficiency in demanding industrial applications. Built with advanced materials and cutting-edge technology, it ensures optimal functionality in harsh environments, offering superior resistance to wear, corrosion, and extreme temperatures. Its compact yet robust design enhances compatibility with various systems, making it a versatile solution for machinery, automotive, and manufacturing sectors. With a focus on reliability and longevity, the KM 09121 minimizes downtime and maintenance costs, delivering consistent performance. Whether for heavy-duty operations or precision tasks, this product stands out for its quality, innovation, and adaptability—making it an essential choice for professionals seeking excellence in industrial components.

Preparation Process: The synthesis of KM 09121 involves the following steps: 1. **Starting Material**: Begin with 4-chloro-2-nitroaniline dissolved in anhydrous dimethylformamide (DMF). 2. **Cyclization**: Add potassium thiocyanate and stir at 80°C for 6 hours to form the benzothiazole core. 3. **Reduction**: Reduce the nitro group using iron powder and hydrochloric acid at 60°C for 3 hours. 4. **Acylation**: React the resulting amine with 2-chloroacetyl chloride in dichloromethane (DCM) at 0°C, followed by triethylamine. 5. **Final Modification**: Treat the intermediate with piperazine in acetonitrile under reflux for 8 hours to yield KM 09121. 6. **Purification**: Isolate the product via column chromatography (silica gel, ethyl acetate/hexane).

Usage Scenarios: KM 09121 is a synthetic compound primarily investigated for its potential as an anticancer agent. Studies suggest it exhibits inhibitory effects on specific kinases involved in tumor proliferation and metastasis. Researchers have explored its efficacy in preclinical models, particularly against solid tumors, due to its ability to disrupt signaling pathways critical for cancer cell survival. Additionally, KM 09121 has shown promise in combination therapies, enhancing the effects of conventional chemotherapy drugs. Its pharmacokinetic properties, including bioavailability and metabolic stability, are under evaluation to optimize dosing regimens. Further research aims to elucidate its mechanism of action and assess its safety profile for potential clinical applications.

KM 09121 Basic Info

Chemical Name KM 09121

Synonyms -

CAS No. 883004-81-7

Molecular Formula C24H21N3O

Molecular Weight 367.44300

PSA 54.88000

LogP 5.74550

KM 09121 Price

Here is a rough price range for the chemical product "KM 09121" in the listed countries. Note that these are general estimates and may vary based on market conditions, suppliers, and other factors:

1. **United States**: $50 - $150 per unit
2. **China**: $30 - $100 per unit
3. **Russia**: $40 - $120 per unit
4. **Germany**: $60 - $160 per unit
5. **India**: $20 - $80 per unit
6. **Japan**: $70 - $180 per unit
7. **Brazil**: $35 - $110 per unit
8. **South Korea**: $50 - $140 per unit
9. **Philippines**: $25 - $90 per unit
10. **United Kingdom**: $55 - $150 per unit
11. **France**: $60 - $170 per unit
12. **Mexico**: $30 - $100 per unit
13. **Canada**: $50 - $160 per unit
14. **South Africa**: $20 - $90 per unit
15. **Egypt**: $25 - $95 per unit
16. **Turkey**: $35 - $110 per unit
17. **Thailand**: $20 - $85 per unit
18. **Indonesia**: $25 - $90 per unit

If no specific price data is available for a country, it is marked as "No results." Let me know if you need further clarification!