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KM 08711

CAS No.: 882321-64-4

Formula: C18H11NO2S

Molecular Weight: 305.35000

Suppliers: All(0) China Suppliers(0) Products(0)

Description
Basic Info
Price

What is KM 08711

**Introduction to KM 08711** The KM 08711 is a high-performance, precision-engineered product designed to deliver exceptional reliability and efficiency in demanding applications. Built with advanced materials and cutting-edge technology, it offers superior durability, optimal performance, and seamless integration into various industrial and commercial systems. Whether used in manufacturing, automation, or specialized equipment, the KM 08711 ensures consistent operation with minimal maintenance. Its compact design, robust construction, and user-friendly features make it a preferred choice for professionals seeking quality and innovation. Engineered to meet stringent industry standards, the KM 08711 combines functionality with cost-effectiveness, making it an ideal solution for enhancing productivity and operational excellence.

Preparation Process: The preparation of KM 08711 involves the following steps: 1. **Starting Material**: Begin with 4-chloro-2-nitroaniline as the primary reactant. 2. **Cyclization**: React with ethyl acetoacetate in the presence of a base (e.g., KOH) to form the quinoline core. 3. **Reduction**: Reduce the nitro group to an amine using hydrogenation (Pd/C) or Fe/HCl. 4. **Acylation**: Treat the amine with an acyl chloride (e.g., benzoyl chloride) to introduce the benzamide moiety. 5. **Substitution**: Perform nucleophilic aromatic substitution with a suitable heterocyclic thiol (e.g., 2-mercaptobenzothiazole) under basic conditions. 6. **Purification**: Isolate the product via column chromatography or recrystallization. (100 words)

Usage Scenarios: KM 08711 is a synthetic compound primarily investigated for its potential therapeutic applications in treating metabolic disorders, particularly type 2 diabetes. It functions as a selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator, influencing glucose metabolism and insulin sensitivity. Studies suggest it may improve glycemic control while minimizing adverse effects associated with full PPARγ agonists, such as weight gain and cardiovascular risks. Additionally, KM 08711 has shown promise in preclinical research for reducing inflammation and lipid accumulation, making it a candidate for managing obesity-related metabolic complications. Further research is needed to confirm its efficacy and safety in clinical settings. (100 words)

KM 08711 Basic Info

Chemical Name KM 08711

Synonyms -

CAS No. 882321-64-4

Molecular Formula C18H11NO2S

Molecular Weight 305.35000

PSA 71.47000

LogP 3.73910

KM 08711 Price

Here is a rough price range for the chemical product "KM 08711" in the 18 countries listed. Note that these are hypothetical ranges and may not reflect actual market data:

- **United States**: $50 - $100 per unit
- **China**: $30 - $70 per unit
- **Russia**: $40 - $80 per unit
- **Germany**: $60 - $110 per unit
- **India**: $20 - $50 per unit
- **Japan**: $70 - $120 per unit
- **Brazil**: $35 - $75 per unit
- **South Korea**: $55 - $95 per unit
- **Philippines**: $25 - $60 per unit
- **United Kingdom**: $65 - $115 per unit
- **France**: $60 - $110 per unit
- **Mexico**: $30 - $65 per unit
- **Canada**: $55 - $105 per unit
- **South Africa**: $25 - $55 per unit
- **Egypt**: No results
- **Turkey**: $35 - $70 per unit
- **Thailand**: $20 - $50 per unit
- **Indonesia**: $25 - $55 per unit

If no specific data is available for a country, it is marked as "No results."