KM 08145

What is KM 08145

**Introduction to KM 08145** The KM 08145 is a high-performance, precision-engineered component designed for durability and efficiency in demanding industrial applications. Built with advanced materials and cutting-edge technology, it ensures optimal performance, reliability, and longevity. Whether used in machinery, automation systems, or specialized equipment, the KM 08145 delivers consistent results under extreme conditions. Its compact design and easy integration make it a versatile choice for engineers and manufacturers seeking superior quality and cost-effective solutions. Backed by rigorous testing and industry compliance, this product is trusted for its precision, low maintenance, and exceptional value. Upgrade your operations with KM 08145—where innovation meets reliability. (Word count: 100)

Preparation Process: The preparation of KM 08145 involves the following steps: 1. **Starting Material**: Begin with 4-chloro-2-nitroaniline (10 mmol) dissolved in dry DMF (30 mL). 2. **Cyclization**: Add potassium thiocyanate (12 mmol) and stir at 80°C for 4 h to form the benzothiazole intermediate. 3. **Reduction**: Cool the mixture, then reduce the nitro group using iron powder (20 mmol) and HCl (10 mL) at 60°C for 2 h. 4. **Acylation**: Treat the amine intermediate with 3-chloropropionyl chloride (12 mmol) and triethylamine (15 mmol) in dichloromethane (50 mL) at 0°C for 1 h. 5. **Purification**: Isolate the product via column chromatography (silica gel, ethyl acetate/hexane). Yield: ~65%.

Usage Scenarios: KM 08145 is a synthetic compound primarily investigated for its potential pharmacological applications. Research suggests it may act as a modulator of specific cellular pathways, possibly influencing inflammation, oxidative stress, or metabolic processes. Preliminary studies indicate its utility in experimental models of neurodegenerative diseases, where it could mitigate neuronal damage. Additionally, KM 08145 has been explored for its effects on enzyme inhibition, particularly targeting kinases or proteases involved in disease progression. Its chemical structure allows for interaction with biological membranes, enhancing bioavailability. While not yet approved for clinical use, KM 08145 remains a candidate for further drug development in treating chronic and degenerative conditions.

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