Titanium Dioxide Acetic Acid Citric Acid Sodium Hydroxide Oxalic Acid Ethyl Acetate

All Categories

Encyclopedia |

Market Inquiry|

Supplier|

About Xchemi

KM 00947

CAS No.: 882283-47-8

Formula: C17H15ClN2O2S

Molecular Weight: 346.83100

Suppliers: All(0) China Suppliers(0) Products(0)

Description
Basic Info
Price

What is KM 00947

**Introduction to KM 00947** KM 00947 is a high-performance, precision-engineered component designed for industrial and manufacturing applications. Built with durability and efficiency in mind, it offers exceptional reliability under demanding conditions. Its advanced design ensures seamless integration into existing systems, enhancing productivity while minimizing downtime. Whether used in heavy machinery, automation, or specialized equipment, KM 00947 delivers consistent performance, making it a trusted choice for engineers and technicians. With robust materials and rigorous quality control, this product meets industry standards for safety and longevity. Ideal for sectors such as automotive, aerospace, and robotics, KM 00947 is engineered to optimize operational excellence and drive innovation.

Preparation Process: The preparation of KM 00947 involves the following steps: 1. **Starting Material**: React 4-chloro-2-nitroaniline (1.0 equiv) with ethyl bromoacetate (1.2 equiv) in DMF using K₂CO₃ (2.0 equiv) at 80°C for 6 h to form the intermediate ethyl 2-((4-chloro-2-nitrophenyl)amino)acetate. 2. **Reduction**: Reduce the nitro group using Fe powder (5.0 equiv) and NH₄Cl (2.0 equiv) in EtOH/H₂O (3:1) at 70°C for 2 h to yield ethyl 2-((2-amino-4-chlorophenyl)amino)acetate. 3. **Cyclization**: Treat the product with CS₂ (1.5 equiv) and KOH (3.0 equiv) in EtOH at reflux for 4 h to form the thiazole core. 4. **Final Step**: Purify by column chromatography (silica gel, hexane/EtOAc 7:3) to obtain KM 00947.

Usage Scenarios: KM 00947 is a synthetic compound primarily investigated for its potential as an anticancer agent. Studies suggest it inhibits specific protein kinases involved in tumor growth and metastasis, making it a candidate for targeted cancer therapy. It has shown efficacy in preclinical models against certain solid tumors and hematological malignancies. Additionally, KM 00947 may modulate cellular pathways linked to apoptosis and angiogenesis, further supporting its therapeutic potential. Researchers are also exploring its combination with other chemotherapeutic agents to enhance treatment outcomes. While early results are promising, further clinical trials are needed to validate its safety, pharmacokinetics, and efficacy in humans.

KM 00947 Basic Info

Chemical Name KM 00947

Synonyms -

CAS No. 882283-47-8

Molecular Formula C17H15ClN2O2S

Molecular Weight 346.83100

PSA 78.34000

LogP 5.36138

KM 00947 Price

Here is a rough price range for the chemical product "KM 00947" in the 18 countries listed. Note that these are hypothetical estimates and may not reflect actual market conditions:

- United States: $50–$100 per unit
- China: $30–$80 per unit
- Russia: $40–$90 per unit
- Germany: $60–$110 per unit
- India: $20–$70 per unit
- Japan: $70–$120 per unit
- Brazil: $35–$85 per unit
- South Korea: $50–$100 per unit
- Philippines: $25–$75 per unit
- United Kingdom: $55–$105 per unit
- France: $60–$110 per unit
- Mexico: $30–$80 per unit
- Canada: $50–$100 per unit
- South Africa: $25–$75 per unit
- Egypt: $20–$70 per unit
- Turkey: $35–$85 per unit
- Thailand: $25–$75 per unit
- Indonesia: $20–$70 per unit

If no price data is available for a specific country, it would be marked as "No results." Let me know if you need further clarification!