Kojic Acid (CAS 501-30-4) is a natural, fungal-derived compound (C₆H₆O₄) widely used in cosmetics for its skin-lightening properties. It inhibits melanogenesis by chelating copper ions in tyrosinase, a key enzyme in melanin production, effectively reducing hyperpigmentation, age spots, and melasma . Commonly incorporated into creams, serums, and masks at 0.5%-2% concentrations, it is favored as a safer alternative to hydroquinone .
Regulatory frameworks vary: the EU's SCCS flagged safety concerns at 1% in 2021 , while the Cosmetic Ingredient Review (2025) deemed it safe ≤1% in leave-on products, citing minimal systemic absorption
. However, potential skin sensitization and instability under light/heat necessitate formulation with stabilizers (e.g., antioxidants) .
Synergistic with vitamin C, arbutin, and glycolic acid, it enhances efficacy in multi-action brightening formulations . Approved in Japan as a quasi-drug and regulated under China's 2021 Cosmetic Ingredient Directory, it remains a cornerstone in global skincare despite evolving compliance requirements.
Specifications:
Appearance: Almost White Crystal.
Purity: 99.0%MIN
Melting Point: 152~156℃
Loss on Drying: 1.0%MAX
Residue on Ignitiion: 0.2%MAX
Chloride: 100mg/kg MAX
Heavy Metals(As Pb): 0.001%MAX(Not Detected)
Iron: 0.001%MAX(Not Detected)
Arsenic: 0.0001%MAX(Not Detected)
Microbiological Test: Accord with demand